Angiogenesis in cutaneous disease: Part II

[摘要] This review will discuss the role of angiogenesis in specific cutaneous diseases. Scientific evidence now points to the role of angiogenesis in tumor development and many other cutaneous disorders. Angiogenesis is a complex process that involves angiogenic growth factors and inhibitors, many of which could be a potential target for pharmacologic intervention. Antiangiogenic agents have recently been applied to derrnatologic diseases with promising efficacy. (J Am Acad Dermatol 2009;61:945-58.) Learning objectives: After completing this learning activity, participants should be able to recognize cutaneous diseases where angiogenesis is likely to be an important factor, recognize scenarios where with traditional therapies, and be able to use angiogenic-angiogenic therapy may be useful in conjunction mediating agents in the treatment of dermatologic disease.

[发布日期] 2009-12-01

[关键词] angiogenesis;antiangiogenic agents;dermatology