Deposition of bioactive gelatin coatings on porous titanium: Influence of processing parameters, size and pore morphology

[摘要] In this work porous commercially pure Ti substrates fabricated by spacer-holder technique (50 vol% NH4HCO3 and three range pores sizes, 100-200 mu m, 250-355 mu m and 355 500 mu m) were coated with two types of gelatinous materials, one as a linear polymer (non-crosslinked) and another one crosslinked. The role of the crosslink, as well as the morphology, size and degree of interconnectivity of gelatins coatings on their tribomechanical behavior (P-h curves and scratch tests) were analyzed. Results revealed a new promising route to manufacture composite porous implants which are potential candidates to develop new treatments, not only for osteochondral defects, but also for other types of damages involving tissues of different nature (hard and soft) perfectly joined.

[发布日期] 2021-09-15

[关键词] Biphasic implant;Osteochondral defects;Porous titanium substrates;Gelatin coating;Structural characterization;Tribomechanical behavior