Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system

[摘要] Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.

[发布日期] 2020-11-01

[关键词] Dynamic chemical labelling (DCL);Drug-induced liver injury (DILI);miRNA-122;Luminex MAGPIX;Liquid biopsy