被撤回的出版物: Simultaneous micellar electrokinetic chromatography and liquid chromatography of adriblastina and tarabine PFS - Their application to some biological fluids (Retracted article. See vol. 78, pg. 1508, 2009)

[摘要] The current work presents analytical procedures for simultaneous determination of tarabine PFS and adriblastina by micellar electrokinetic chromatography (MEKC) and liquid chromatography (LC). For MEKC analysis, separations and identifications were accomplished using uncoated fused-silica capillary with hydrodynamic injections in the presence of 50 mM borate/phophate pH 8.7 and 100 mM SDS. The migration times of tarabine PFS and adriblastina were found to be 2.70 and 6.40 min, respectively. Calibration curves were established for 10-300 ng/mL (r=0.998) tarabine PFS and for 8-120 mu g/mL (r=0.999) adriblastina. For LC analysis, separations were performed on teicoplanin stationary phase with reversed mobile phase containing methanol:buffer pH 4.05 (20:80%, v/v) at 285 nm. The retention times of tarabine PFS and adriblastina were 5.18 and 7.20 min, respectively. Calibration curves were established for 3-90 mu g/mL (r = 0.998) tarabine PFS and for 10-120 mu g/mL (r = 0.999) adriblastina. Both MEKC and LC methods were applied for the simultaneous determination of analytes in urine samples. (c) 2004 Elsevier B.V. All rights reserved.

[发布日期] 2005-03-31

[效力级别]  Retracted Publication

[关键词] tarabine PFS;adriblastina;MEKC;LC;simultaneous determinations;urine samples