Studies into the synthesis of derivatives of 4-amino-2,3-dihydroisothiazole 1,1-dioxides and 4-amino-1,2-oxathiole 2,2-dioxides: The search for linked pi-system containing analogues as potential inhibitors of HIV-1 reverse transcriptase

[摘要] The synthesis, and anti HIV-1 activity, of new derivatives of 4-amino-1,2-oxathiole 2,2-dioxide (3, 5, 6 and 9) and 4-amino-2,3-dihydroisothiazole 1,l-dioxide (14). a new heterocyclic ring system, is described. (C) 1997 Elsevier Science Ltd.

[发布日期] 1997-12-29