STUDIES TOWARD THE TOTAL SYNTHESIS OF DITERPENES IN THE LABDANE SERIES .3. SYNTHESIS OF 2 EPIMERIC 6,7,8-TRIHYDROXYLABDADIENES

[摘要] The syntheses of 6 beta,7 beta, 8 alpha, and 6 beta, 7 beta, 8 beta-trihydroxy labdadienes, 2a and 2b respectively, were performed starting from the decalin 3, in order to determine the exact structure of compounds, isolated from plant sources, for which configuration at C-8 was not clearly demonstrated. As a result, the structure 2a was established with certainty for crotomachlin, a diterpene from Croton macrostachys.

[发布日期] 1994-02-14