Cation-induced shifts in the proton NMR spectroscopy of dioxydiacetamide ionophores

[摘要] Complexation of 1,2-disubstituted dioxydiacetamides with Group II cations in MeOH-d(4) results in downfield H-1 NMR shifts. These cation induced shifts (CATIS) can be used to estimate the stoichiometry of cation/ligand binding. The shifts decrease in the order: Ca2+>Mg2+>Sr2+>Ba2+ while the order of binding is Ca2+>Sr2+>Ba2+>>Mg2+. The shifts are independent of the nature of the anion except for Mg2+ where the CATIS decreases in the order: I>Br>Cl>ClO4-. (C) 1997 Elsevier Science Ltd.

[发布日期] 1997-12-22