CH3CO2H-prompted three components tandem reaction: An efficient and practical approach to trisubstituted pyrrolo[1,2-a]pyrazines

[摘要] An efficient protocol for the synthesis of trisubstitued pyrrolo[1,2-a]pyrazines through three components cyclization and one-pot cascade reaction is presented. Various trisubstitued pyrrolo[1,2-a]pyrazines are obtained by this metal-free process in moderate to good yields. (C) 2017 Published by Elsevier Ltd.

[发布日期] 2017-12-21

[关键词] Metal-free;Pyrrolo[1,2-a]pyrazines;Cascade reaction