A convenient and mild cyclocondensation using water-soluble aldehydes in water

[摘要] The use of negatively charged aluminosilicate layers and Lewis acidic cations embedded therein allowed efficient cyclocondensation of bisamines with water-soluble aldehydes to be achieved in water. The protocol does not involve acidic or reflux conditions, thereby avoiding undesired byproduct formation. The use of water as a reaction medium is indispensable to ensure high reaction yields. (C) 2018 Elsevier Ltd. All rights reserved.

[发布日期] 2018-12-20

[关键词] Reaction in water;Montmorillonite;Cyclocondensation;Thiazide;Ytterbium