Disproportionation reaction of diarylmethylisopropyl ethers: a versatile access to diarylmethanes from diarylcarbinols speeded up by the use of microwave irradiation

[摘要] An efficient synthesis of diarylmethanes under classical thermal conditions and under microwave heating is described from diarylcarbinols via a new disproportionation reaction. The key step involves a selective hydride transfer of isopropyl ether intermediates. Mild reaction conditions i.e., catalytic CBr4 or TfOH in i-PrOH and good yields render this method useful and competitive to the conventional approaches relying on application of external reducing agents. (c) 2006 Elsevier Ltd. All rights reserved.

[发布日期] 2006-12-18

[关键词] disproportionation;diarylcarbinols;diarylmethanes;i-PrOH;CBr4;TfOH;microwave heating