Modelling of EnFETs for the creatinine detection
[摘要] Creatinine enzymatic field effect transistors (C-EnFETs) realised from a pH-sensitive field effect transistor (pH-ISFET) have been modelled by taking into account the enzymatic reaction, the diffusion phenomena of the main chemical species in the electrolyte, the related acid/basic chemical reactions in watery solution and the detection properties of the pH-ISFET sensitive gate. Thus, the concentrations of the main chemical species have been characterized near the sensitive gate, and the C-EnFET micro sensor detection properties have been studied according to the most influential parameters. A good fit has been shown between modelling and experimental results. The model has been developed for the optimization of creatinine-EnFETs in the field of haemodialysis, but is also fully compatible for other EnFETs based on pH-ISFET-metry. (c) 2006 Elsevier B.V. All rights reserved.
[发布日期] 2006-10-25 [发布机构]
[效力级别] Proceedings Paper [学科分类]
[关键词] modelling;EnFETs;creatinine detection [时效性]