Development of a positron emission tomography radiopharmaceutical for imaging thymidine kinase gene expression: Synthesis and in vitro evaluation of 9-{(3-[F-18]fluoro-1-hudroxy-2-propoxy)methyl}guanine

[摘要] 9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]guanine (FHPG) 2 has been labeled with fluorine-18 and evaluated in vitro as a potential radiotracer for mapping gene expression in vivo with positron emission tomography (PET). (C) 1997 Elsevier Science Ltd.

[发布日期] 1997-07-22