DESIGN, SYNTHESIS AND ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS OF NON-PHOSPHORYLATABLE ANALOGS OF TOYOCAMYCIN, SANGIVAMYCIN AND THIOSANGIVAMYCIN

[摘要] A number of 7-alkyl 4-aminopyrrolo[2,3-d]pyrimidine derivatives related to toyocamycin, sangivamycin and thiosangivamycin have been prepared and tested for their activity against human cytomegalovirus (HCMV). Only the thioamide substituted derivatives demonstrated biological activity.

[发布日期] 1992-12-01