RESOLUTION OF N-PROTECTED AMINO-ACID DERIVATIVES IN SUPERCRITICAL CARBON-DIOXIDE CATALYZED BY ALCALASE

[摘要] Alkaline protease ''alcalase'' has been found to be very stable and active in supercritical carbon dioxide. Procedures for resolution of N-protected amino acid derivatives in supercritical carbon dioxide catalyzed by alcalase with high yields and optical purity have been developed.

[发布日期] 1994-02-24