A model for the taxol (paclitaxel)/epothilone pharmacophore

[摘要] Epothilone is a recently discovered compound that appears to bind at the same microtubule-binding site as the anticancer agent taxol. A model for the pharmacophore common to these structurally dissimilar compounds is presented. Copyright (C) 1996 Elsevier Science Ltd

[发布日期] 1996-12-17