TRPML and lysosomal function

[摘要] Mucolipm I (MLNI), also known as TRPMLI, is a member of the mucolipin family. The mucolipins are the only lysosomal proteins within the TRP superfamily. Mutations in the gene coding for TRPML I result in a lysosomal storage disorder (LSD). This review summarizes the current knowledge related to this protein and the rest of the mucolipin family. (c) 2007 Elsevier B.V. All rights reserved.

[发布日期] 2007-08-01

[关键词] lysosomal storage disorder;mucolipin protein family;endocytosis and lysosomal function;mucolipidosis