APPLICATION OF N,S-CHELATING CHIRAL ZINC BIS(ARENETHIOLATE) COMPLEXES AS NEW PRECURSOR CATALYSTS IN THE ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES

[摘要] The addition of diethylzinc to aldehydes in the presence of a catalytic amount of enantiomerically pure N,S-chelated bis{2-[(R)-1-(dimethylamino)ethyl]phenylthiolato}zinc afforded the corresponding secondary alcohols in neatly quantitative yields with optical purities of up to 99 % e.e. under mild reaction conditions.

[发布日期] 1994-08-29