Synthesis of the 6′-iso analogues of neplanocin A and 5′-homoneplanocin A

[摘要] An efficient synthesis of 6'-isoneplanocin A and 6'-isohomoneplanocin A is reported. The key steps in the synthesis include an enyne metathesis and a regioselective oxidation. (c) 2009 Elsevier Ltd. All rights reserved.

[发布日期] 2009-12-23

[关键词] Carbocyclic nucleosides;Grubbs reaction;Mitsunobu reaction