Recent advancements in the synthesis of pentafluorosulfanyl (SF5)-containing heteroaromatic compounds

[摘要] The unique features of the pentafluorosulfanyl (SF5) group have made it renowned as a super trifluoromethyl (CF3) group. Owing to the big success of CF3-containing heteroaromatic compounds in medicinal chemistry, agro-chemistry and material sciences, SF5-substituted heteroaromatic compounds have gained a lot of attention in very recent years as novel and potential candidates in these fields. However, the synthetic methodology for SF5-substituted heteroaromatic compounds is still highly limited. This digest highlights the recent, rapid, and significant advances made in the synthesis of SF5-heteroaromatics. (C) 2017 Elsevier Ltd. All rights reserved.

[发布日期] 2017-12-27

[关键词] Pentafluorosulfanyl;Fluorine;Sulfur;Trifluoromethyl;Heteroaromatics