Absolute configurations of griseorhodins A and C (vol 50, pg 4721, 2017)

[摘要] The known antibiotic and cytotoxic compounds griseorhodin A (1) and griseorhodin C (2) were produced in solid culture by Streptomyces puniceus AB10, which was isolated from the leaf-cutter ant Acromyrmex rugosus rugosus. Their absolute configurations were unambiguously established as 6S,6aS,7S,8S and 6R,6aS,7S,8R, respectively, using vibrational circular dichroism (VCD) and density functional theory (DFT) calculations. (C) 2018 Elsevier Ltd. All rights reserved.

[发布日期] 2018-03-28

[关键词] Streptomyces puniceus;Acromyrmex rugosus rugosus;Rubromycin;Griseorhodins;Vibrational circular dichroism