SYNTHESIS AND REACTIVITY OF THE FIRST BIS(CROWN ETHER) ENEDIYNE

[摘要] The synthesis of a new bis(crown ether)-enediyne 3 via palladium catalyzed coupling reactions is described. On treatment with sodium-hexafluorophosphate two cations are bound by the title compound 3; with potassium ions the sandwich complex 5 is formed. The thermal reactivity of the enediyne moiety towards cyclisation was investigated by differential scanning calorimetry, whereby the metal complexes showed an increased stability.

[发布日期] 1994-05-23