Carbonyl reduction with CaH2 and R3SiCl catalyzed by ZnCl2

[摘要] Ketones and aldehydes were effectively reduced to the corresponding alcohols (or their silyl ethers) by the reaction with CaH2 and R3SiCl in the presence of a catalytic amount of ZnCl2. In the absence of the carbonyl substrate, the reagent reduced R3SiCl to the corresponding hydrosilane under mild reaction conditions. (C) 2007 Elsevier Ltd. All rights reserved.

[发布日期] 2007-12-24