DETERMINATION OF ENANTIOMERIC PURITY OF HYDROXY BIARYLS USING H-1 AND P-31-NMR ON THEIR DIAZAPHOSPHOLIDINE DERIVATIVES

[摘要] Chiral biaryl alcohols were readily transformed in a single step, with chiral nonracemic 1,2-diamines, PCl3, and sulfur in CDCl3 - all in a NMR tube - to their diastereomeric diazaphospholidines and their diastereomeric ratios (also ee's) assessed directly.

[发布日期] 1994-07-18