Iron(III) p-toluenesulfonate catalyzed synthesis of homoallyl ethers from acetals and aldehydes

[摘要] Iron(III) p-toluenesulfonate, Fe(OTs)(3)center dot 6H(2)O, is an inexpensive, versatile and commercially available catalyst for the allylation of acetals using allyltrimethylsilane to yield homoallyl ethers in moderate to good yields. The one-pot conversion of aldehydes to homoallyl ethers using alkoxysilanes has also been accomplished using Fe(OTs)(3)center dot 6H(2)O as a catalyst. The use of mild reaction conditions and a relatively non-corrosive catalyst make this method an attractive option for the synthesis of a range of homoallyl ethers. (C) 2007 Elsevier Ltd. All rights reserved.

[发布日期] 2007-12-03