DIASTEREOSELECTIVE SYNTHESIS OF SYN-BETA-METHYL HOMOALLYL ALCOHOLS WITH CROTYLMOLYBDENUM COMPLEXES

[摘要] Air stable (cyclopentadienyl)Mo(NO)(halide)[eta-3-(Z)-crotyl] complexes add to aldehydes with high diastereoselectivity to yield syn-beta-methyl homoallyl alcohols in up to 98% de. New routes to these reactive metal-(Z)-crotyl reagents utilize 2-butyne and s-cis-butadiene organomolybdenum intermediates instead of (Z)-crotylpotassium.

[发布日期] 1991-03-04