Microwave-assisted methods for the synthesis of pentacyclo[5.4.0.02,6.03,10.05,9]undecylamines

[摘要] Efficient methodologies for the preparation of pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecane (PCU) amine derivatives are described via microwave-assisted synthesis. The obtained results revealed that microwave-assisted synthetic procedures under controlled conditions (power, temperature and time) are very convenient, high yielding, efficient and low-cost methods for the preparation of PCU amine derivatives. The new methods show several advantages including operational simplicity, good performance, significant reduction in reaction time, less by-product formation and easier purification. (C) 2013 Elsevier Ltd. All rights reserved.

[发布日期] 2013-12-11

[关键词] Pentacycloundecane derivatives;Microwave-assisted synthesis;Polycyclic cage