Intramolecular cyclization of aryl substituted iodonium ylides with copper(I) chloride

[摘要] Cu(I)Cl decomposition of the phenyliodonium ylides derived from o-, m- and p-methoxyphenyl-3-ketopentanoic acid methyl esters affords the corresponding 5-, 6- and 7-methoxy-1-carbomethoxy-2-tetralones in preparative yields. The lower homologous phenyliodonium ylides derived from o-, m- and p-methoxyphenyl-3-ketobutyric acid methyl esters yield the analogous 1-carbomethoxy-2-indanone only in the meta-methoxyphenyl case, and the ortho- and para-methoxyphenyl substituted iodonium ylides yield dimeric products. (C) 1997 Elsevier Science Ltd.

[发布日期] 1997-06-23