Biomimetic self-condensation of malonates mediated by nucleosides

[摘要] Nucleoside mediated Claisen condensation of malonates has been achieved under biomimetic weak acid conditions, pH 3 or 4, 0.15M NaCl, and 0.125M Mg2+. The result illustrates the catalyzing property of end-nucleosides of t-RNA in the RNA world. (C) 2007 Elsevier Ltd. All rights reserved.

[发布日期] 2007-11-05