Solid phase synthesis of 2,3-dihydro-4-pyridones: Reaction of Danishefsky's diene with polymer-bound imines

[摘要] An efficient method for the construction of 2,3-dihydro-4-pyridones on solid support has been developed, which utilized the Lewis-acid catalyzed tandem Mannich-Michael reaction of Danishefsky's diene with polymer-bound aldimines. (C) 1997 Elsevier Science Ltd.

[发布日期] 1997-06-09