A novel 5'-iodonucleoside allows efficient nonenzymatic ligation of single-stranded and duplex DNAs

[摘要] A new iodothymidine phosphoramidite enables the placement of a 5'-iodide into oligonucleotides; the iodide is stable to ammonia deprotection and allows nonenzymatic ligations of DNA. (C) 1997 Elsevier Science Ltd.

[发布日期] 1997-08-11