Microwave-assisted aminolysis of vinylepoxides

[摘要] Di- and trisubstituted vinylepoxides in NH4OH were subjected to microwave irradiation affording the corresponding vicinal aminoalcohols in high yields. The reaction is stereospecific and highly regioselective for addition at the allylic carbon. (C) 1999 Elsevier Science Ltd. All rights reserved.

[发布日期] 1999-12-24

[关键词] aminoalcohols;aminolysis;microwave heating;ring-opening;vinylepoxides