The roles of T cells in psoriasis
[摘要] Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on the skin. It affects approximately 3% of the US population and is associated with histological changes such as epidermal hyperplasia, increased blood vessel proliferation, and infiltration of leukocytes into the skin’s dermis. T cells, which are classified into various subtypes, have been found to play significant roles in immune-mediated diseases, particularly psoriasis. This paper provides a review of the different T lymphocyte subtypes and their functions in psoriasis, as well as an overview of targeted therapies for treating psoriasis.
[发布日期] 2023-10-24 [发布机构]
[效力级别] [学科分类]
[关键词] psoriasis;T lymphocytes;cytokines;targeted therapies;immunology [时效性]