Sensor-augmented CSII therapy with predictive low-glucose suspend following total pancreatectomy

[摘要] Pancreatogenic diabetes is characterised by recurrent severe hypoglycaemia due to changes in both endocrine andexocrine functions. There are no guidelines to manage these individuals. Herein, we describe the post-operativemanagement of two people who developed pancreatogenic diabetes following total pancreatectomy for neuroendocrinemalignancy. In both individuals, diabetes was managed using sensor-augmented predictive low-glucose suspendcontinuous subcutaneous insulin infusion (CSII). We demonstrate the benefit of sensor-augmented CSII in avertinghypoglycaemia whilst optimising glycaemic control. Expected rates of severe hypoglycaemia in individuals withpancreatogenic diabetes can be averted with the use of continuous glucose monitoring (CGM) technology, optimisingquality of life and reducing the risk of diabetes-related complications.

[学科分类] 血液学