Non-functional duodenal neuroendocrine carcinoma: a rare cause of diabetes mellitus

[摘要] 8 g/dL and Whipple’s pancreatico-duodenectomy was undertaken. This showed a well-differentiated neuroendocrine carcinoma arising in duodenum (Grade G1 with Ki67: 0.5%), with areas of chronic pancreatitis and preservation of pancreatic islet cells. There was complete resolution of diabetes post Whipple’s procedure and patient was able to come of insulin treatment. Her last HBA1C was 31 mmol/mol, 4 months post tumour resection. Learning points: Diabetes mellitus and malignancy can be related. A high index of suspicion is needed when diabetes mellitus presents atypically. Non-functional neuroendocrine tumours can present with diabetes mellitus.

[学科分类] 血液学