Newly introduced repurposing topical ozenoxacin against grade-II acne vulgaris: a case series

[摘要] To assess the efficacy and safety of a newer fluorine-free quinoline class topical antibiotic, ozenoxacin (1%), as a topical monotherapy in grade-II acne vulgaris (AV). Five female patients between the age group of 18–25 years with grade-II AV were prescribed twice daily topical ozenoxacin (1%) in cream formulation as a monotherapy. The efficacy was analyzed using the visual analog scale and investigator global assessment scoring system. At 4 weeks of treatment follow-up, we observed that the pretreatment and posttreatment visual analog scale and investigator global assessment scores showed remarkable differences with excellent response in all five patients without any adverse effects. The above case series concluded that 1% ozenoxacin could be used as an alternative, potential, and safer topical treatment modality in grade-II AV patients.

[学科分类] 皮肤病学

[关键词] acne vulgaris;investigator global assessment;ozenoxacin;topical antibiotic;visual analog scale