Synthesis and characterization of highly substituted pyrazoles using silicaphosphoric acid nanoparticles as a recoverable heterogeneous solid acid catalyst

[摘要] Highly substituted pyrazoles have been prepared by condensing 1,3-diketones and various hydrazine derivatives using silica-phosphoric acid nanoparticles (nano-SPA). This nano solid catalyst has been prepared by the reaction of nano silica chloride with dry phosphoric acid. This green methodology has advantages such as short reaction times, simple work-up, high efficiency, reusability of the catalyst and no use of any solvents.

[学科分类] 化学（综合）

[关键词] Highly substituted pyrazoles;Heterogeneous;Nano silica-phosphoric acid;Solid acid catalyst;Article