Role of Bcl-3 in solid tumors

[摘要] Bcl-3 is an established oncogene in hematologic malignancies, such as B-cell chronic lymphocytic leukemias. Nevertheless, recent research has shown that it also participates in progression of diverse solid tumors. The present review summarizes the current knowledge of Bcl3 role in solid tumors progression, including some new insights in its possible molecular mechanisms of action.

[发布日期] 2011-12-23

[关键词] Mouse Mammary Tumor Virus;Skin Adnexa;Antiapoptotic Gene BCL2;Upstream Signal Transduction;Diminish Cell Death