Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes

[摘要] We published a new method (BMC Bioinformatics 2014, 15:14) for searching for differentially expressed genes from two biological conditions datasets. The presentation of theorem 1 in this paper was incomplete. We received an anonymous comment about our publication that motivates the present work. Here, we present a complementary result which is necessary from the theoretical point of view to demonstrate our theorem. We also show that this result has no negative impact on our conclusions obtained with synthetic and experimental microarrays datasets.

[发布日期] 2016-11-15

[关键词] Differentially expressed genes;Fold change;Average of ranks