Healthy aging—would cytotoxic T lymphocytes stand out?

[摘要] t cells (SnCs) accumulate in multiple tissue types with the process of individual aging, hindering tissue renewal and driving multiple aging-related disorders. Aside from senescence-associated secretory phenotype (SASP) neutralization and senolytics, there is an emerging senolysis strategy to eliminate SnCs by mobilizing the immunosurveillance function of cytotoxic T lymphocytes (CTLs).

[发布日期] 2023-10-17