Using water-soluble C60 fullerenes in anticancer therapy

[摘要] Growth experiments of transplanted malignant tumors in the presence of water-soluble C60 fullerenes were performed on groups of mice. It was found that C60 fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant activity and the blocking of the specific cell receptors (for example, endothelial growth factor). The findings demonstrate the possibility of using C60 fullerenes in anticancer therapy.

[发布日期] 2011-08-19

[关键词] C fullerenes;Mice line C57Bl/6J;Lewis lung carcinoma;Tumor growth inhibition;Increasing of animal life;Survival of animals;Metastasis inhibition index;Histological data