Measures Derived from a 2 x 2 Table for an Accuracy of a Diagnostic Test

[摘要] Diagnostic test studies are receiving increasing attention, but are rather challenging to identify efficiently and reliably. Health care professionals seek information regarding the best available evidence on test accuracy, and there is also a growing requirement to understand the measures of diagnostic tests. An outcome of epidemiological studies, diagnostic tests, and comparative therapeutic trails are often presented in the form of 2 x 2 tables. The analysis from these tables and its significance must be interpreted correctly, so as to answer the clinical research questions of the studies. This article discusses about the measures which could be derived from a 2x2 table format, for a diagnostic test situation, where the interest is to observe the relationship between two qualitative (nominal) variables.

[关键词] 2 x 2 contingency table;Sensitivity;Specificity;Likelihood ratio;Predictive values;Diagnostic odds ratio;Youden?s index.