Synthesis of Calix[4]arene Appended Lactosylated G1 and Galacto­sylated G2 Generation Glycodendrimers using a ‘CuAAC’ Click Approach

[摘要] A modular and highly reliable click approach is applied for the expeditious synthesis of lactose- and galactose-coated calixarene-cored G1 and G2 generation glycodendrimers, respectively. The developed calixarene glycodendrimers have been characterized by using extensive spectral analysis including NMR (1H and 13C), MS, IR, and SEC data.

[学科分类] 精神健康和精神病学

[关键词] azide;alkyne;click reaction;calix[4]arene;macrocyclic;glycodendrimer;catalysis