Red-Shifting Blue Light Photoredox Catalysis for Organic Synthesis: A Graphical Review

[摘要] Photoredox catalysis has revolutionized synthetic chemistry in recent decades. However, the field has traditionally used high-energy blue/ultraviolet light to activate chromophores. High-energy irradiation is associated with several drawbacks (e.g., activation of sensitive functional groups, undesired metal-ligand homolysis, background activation of molecules, and poor penetration), which has led researchers to develop alternative systems with lower energy deep red (DR) or near-infrared (NIR) light. This graphical review provides a concise overview of photophysical principles relevant to photoredox catalysis. Several applications that benefit from low-energy irradiation, such as large-scale batch reactions, photodynamic therapy, biological labeling, and multi-photon excitation are reviewed.

[学科分类] 精神健康和精神病学

[关键词] photoredox catalysis;deep red and near-infrared light;cross-coupling;reaction engineering;photodynamic therapy;photoaffinity labeling;proximity labeling;multiphoton excitation