Antifungal activity of liriodenine on agents of systemic mycoses, with emphasis on the genus Paracoccidioides

[摘要] Background: Endemic systemic mycoses remain a health challenge, since these opportunistic diseases are increasingly infecting immunosuppressed patients. The simultaneous use of antifungal compounds and other drugs to treat infectious or non-infectious diseases has led to several interactions and undesirable effects. Thus, new antifungal compounds should be investigated. The present study aimed to evaluate the activity of liriodenine extracted from Annona macroprophyllata on agents of systemic mycoses, with emphasis on the genus Paracoccidioides .

[学科分类] 药理学

[关键词] Liriodenine;Paracoccidioidomycosis;Systemic mycosis;Antifungal compounds;Antimicrobial compounds;Medicinal plants