A Rough Set and Cellular Genetic Fusion Algorithm for Acute Critical Disease Prediction

[摘要] This study is to solve the problems of an overly-broad scale of medical indicators, lack of retrospective research samples, insufficient depth of data mining, and low disease prediction accuracy. In this paper, we propose an intelligent screening algorithm that combines a genetic algorithm, cellular automata, and rough set theory. This algorithm can achieve high accuracy in predicting patient outcomes with a small number of indicators. And we compare it with the traditional genetic algorithm. We built the prediction model with 64 indicators based on the logistic regression (AUC 0.8628), support vector machine (AUC 0.5319), Naïve Bayes (AUC 0.7102), and AdaBoost algorithms (AUC 0.9095). Using the cellular genetic algorithm for attribute screening not only effectively reduces the number of indicators but also achieve almost the same accuracy of prediction with 8 indicators based on the logistic regression (AUC 0.8782), support vector machine (AUC 0.8525), Naïve Bayes (AUC 0.8408), and AdaBoost algorithms (AUC 0.8770). Compared with the traditional scoring system, the predictive model established in this paper can more accurately predict rebleeding accidents based on physiological test indicators and continuous patient indicators.

[学科分类] 计算机科学（综合）

[关键词] cellular genetic algorithm;key indicator;disease prediction;machine learning.