Mesenchymal stem cell-derived exosome as a nano weapon to target the COVID-19 pandemic

[摘要] In these times of despair when a nano-sized organism, the SARS-CoV-2, has rendered the human race helpless, made the global health status decline, and drowned the world economy, a ray of hope comes from another nano-sized particle, the exosome. The potential of mesenchymal stem cells has already been established in COVID-19; however, cell-based therapy has its risks. We thereby propose cell-free therapy using stem cells-derived exosomes to fight against COVID-19, as they can be a game-changer owing to their immunomodulatory nature, which combats the cytokine storm characterizing this disease, and their practical efficiency, which will realistically aid large access to therapy worldwide.

[学科分类] 仪器

[关键词] SARS-CoV-2;Wharton’s Jelly;COVID-19;Cell-free therapy;Exosomes;Immunomodulation