Clinical application of 2.16% hypertonic saline solution to correct the blood sodium concentration in diarrheic calves with hyponatremia

[摘要] The aim of this study was to examine whether 2.16% hypertonic saline solution (HSS) is useful for the treatment of diarrheic calves with hyponatremia. Eleven of 13 female Holstein calves exhibiting moderate diarrhea and hyponatremia received 1,250 m l of 2.16% HSS over 15 min regardless of body weight. The remaining two calves that were unable to stand and had severe hyponatremia received 2,500 m l of 2.16% HSS intravenously over 30 min. As a result, hyponatremia in all diarrheic calves was significantly improved by the administration of 2.16% HSS from 122.2 ± 7.0 mEq/ l at pre to 134.8 ± 3.7 mEq/ l at post, which was above the threshold of 132 mEq/ l for hyponatremia. Therefore, 2.16% HSS may be useful for hyponatremia in calves with diarrhea.

[学科分类] 兽医学

[关键词] 2.16% hypertonic saline solution;calf;diarrhea;hyponatremia