Synthesis and antibacterial evaluation of new heterocyclic system: [1,2,4]triazolo[3′,4′:6,1]pyridazino[4,3-e][1,3,4]thiadiazine

[摘要] A series of 1,2,4-triazolo[3′,4′:6,1]pyridazino[4,3- e ][1,3,4]thiadiazines have been synthesized by intermolecular cycli­zation of a hydrazide derivative with various triethyl ortho­esters. The antibacterial activity of various derivatives of this new heterocyclic system was evaluated.

[学科分类] 内科医学

[关键词] heterocyclization;phenylisothiocyanate;tria­zolopyridazinothiadiazine;triethylorthoester