Convenient way of synthesis and crystal structure of 1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine, a histamine H4 receptor antagonist
[摘要] 1-[(5-Chloro-1 H -indol-2-yl)carbonyl]-4-methylpiperazine (JNJ 7777120) is the known histamine H 4 receptor reference compound. The convenient way of its synthesis and the crystal structure are described.
[发布日期] [发布机构]
[效力级别] [学科分类] 内科医学
[关键词] 1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine (JNJ 7777120);4-(4;6-dimethoxy-1;3;5-triazin-2-yl)-4-methylmorpholinium tetrafluoroborate;amide formation;crystal structure;histamine H4 antagonist [时效性]
