Synthesis of benzyloxycyanophenylboronic esters

[摘要] The synthesis of six new benzyloxycyanoboronic esters: 2-benzyloxy-6-cyanophenyl-4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane ( 4a ), 4-benzyloxy-2-cyanophenyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane ( 4b ), 4-benzyloxy-3-cyanophenyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane ( 8a ), 2-benzyloxy-5-cyanophenyl-4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane ( 8b ), 3-benzyloxy-4-cyanophenyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane ( 12a) , and 2-benzyloxy-5-cyanophenyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane ( 12b ) is reported.

[学科分类] 内科医学

[关键词] benzyloxybenzonitriles;benzyloxycyanoboronic esters;palladium catalyzed cross-coupling